Pregnenolone is a precursor to all the steroid hormones, including DHEA, progesterone, testosterone, and estrogen. It is produced from cholesterol in the mitochondria in the cells in the brain and the adrenal cortex. Pregnenolone stimulates our brain receptors, influencing learning, and is a memory enhancer. It is essential to keeping our brain functioning at its peak capacity. Levels are directly correlated with cognitive ability and decline with age.
Male and female bodies use pregnenolone differently. In women, more of the pregnenolone becomes estrogen while in men more is used to make testosterone. However, on its own, pregnenolone is essential in keeping our brain functioning at its peak capacity and it is found at higher concentrations in the brain than in any other organ in the body, which serves to enhance our mental functions.
Current research is being done to test the benefits of pregnenolone with those suffering from Alzheimer’s disease, conditions such as multiple sclerosis, spinal cord injuries, cardiovascular problems, and for boosting the immune system.